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milbemycin oxime
Milbemycin oxime (trade name Interceptor, marketed by Novartis) is a veterinary drug from the group of milbemycins, used as a broad spectrum antiparasitic. It is active against worms (anthelmintic), insects (insecticide) and mites (miticide).
==Mechanism of action==
Like avermectins, milbemycins are products of fermentation by ''Streptomyces'' species. They have a similar mechanism of action, but a longer half-life than the avermectins. Milbemycin oxime is produced by ''Streptomyces hygroscopicus aureolacrimosus''. It opens glutamate sensitive chloride channels in neurons and myocytes of invertebrates, leading to hyperpolarisation of these cells and blocking of signal transfer.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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